Reviewed By: Dr. John Lekkas
GMC Registration: 7448560
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Wegovy Injection
Medication Features
Wegovy is a once-weekly weight loss injection and has an active ingredient called semaglutide that reduces weight by making you feel less hungry. It assists adults who require additional help alongside healthy eating and physical activity.
You may order Wegovy Weight Loss Injection online from the Mayfair Weight Loss Clinic by filling out a free online consultation form. Our weight management clinical team will assess your medical condition and, if it is suitable for you, prescribe you the injection.
Once the medication is approved by our UK registered prescribers, our team will quickly dispense and deliver your weight loss medication to your doorstep.
What is Wegovy?
Wegovy is a prescription weight loss treatment containing semaglutide, approved by the MHRA and NICE for weight management. Wegovy injection is prescribed for individuals with a BMI of 30 or higher, or 27 or higher with weight-related health conditions like prediabetes or high blood pressure.
Wegovy works by replicating GLP-1, a hormone that helps control appetite, regulate blood sugar, and make you feel fuller for longer. Weight loss injection Wegovy is taken once a week, with a maximum dose of 2.4mg.
Wegovy weight loss treatment helps by:
- Reducing excessive appetite signals
- Slowing the movement of food through the stomach
- Supporting earlier feelings of fullness
- Encouraging more consistent eating patterns
Clincal team recommend using Wegovy alongside healthy eating and exercise for optimal results. It supports weight loss but should not replace lifestyle changes.
Fill out the Online Form
Fill out our online consultation form with valid and accurate patient information and medical conditions.
Select Treatment
Select the weight loss treatment you are prescribed. We will suggest the options based on your eligibility.
Track & Receive
Your treatment will be dispensed and delivered to your doorstep by a tracked courier service.
How much weight could you lose with Wegovy in one year?
* Based on the results of a peer-reviewed clinical study of 2539 participants.
Who is eligible for Wegovy UK?
The clinical team may consider Wegovy injection following a structured medical assessment completed through an online consultation. It is generally appropriate for adults who meet one of the following criteria:
A Body Mass Index (BMI) of 30 or above
A BMI of 27 or above with a weight-related health condition, including:
- Cardiovascular disease
- High blood pressure
- Prediabetes
- Obstructive sleep apnoea
A UK-licensed prescriber confirms final suitability after reviewing your medical information. Always read the patient information leaflet before starting treatment.
How does Wegovy work for weight loss?
Wegovy for weight loss contains semaglutide, a man made version which mirrors the effects of GLP-1 released naturally after eating. This hormone communicates with the brain to signal fullness and helps regulate blood sugar levels.
Through this mechanism, Wegovy:
- Encourages fullness sooner during meals
- Reduces persistent hunger between meals
- Slows digestion to extend satiety
For optimal results, clinical team recommend using Wegovy alongside a calorie-controlled diet and regular physical activity. Clinical evidence shows that many individuals achieved meaningful weight reduction of around 5% when following this combined approach.
How effective is Wegovy for weight loss?
Clinical studies show that consistent use of the Wegovy weight loss pen can support significant weight reduction when taken as prescribed. In long-term 68-week trials, participants using the 2.4mg maintenance dose achieved notably greater weight loss than those receiving placebo.
Clinical trial results showed:
- 86% of participants lost at least 5% of body weight
- 69% achieved a 10% reduction
- 50% lost 15% or more
Researchers also observed reductions in waist measurement and improvements in blood pressure. Individual results vary.
Disclaimer: These outcomes reflect clinical trial data and do not guarantee the same results for every individual.
Expected weight changes across Wegovy dose levels
Weight loss outcomes depend on dose progression, consistency, and lifestyle habits. Higher doses typically provide stronger appetite regulation, although individual responses differ and require clinical review.
Note: These figures are based on a 72-week clinical study comparing treatment outcomes with placebo.
Available Wegovy Dosages and Wegovy Prices UK
Wegovy weight loss injections follows a step-by-step dosing schedule designed to help the body adjust comfortably. Treatment begins at a low dose and increases gradually until the maintenance dose is reached, helping reduce side effects while supporting steady progress. Below, you’ll find the recommended Wegovy pen dosing schedule, along with an overview of Wegovy prices in the UK, which vary depending on dosages.
0.25 mg Cost: £139.00
During the first four weeks, treatment usually starts with a 0.25 mg once-weekly injection to help your body adjust gradually and reduce the likelihood of side effects, while beginning appetite regulation. Cost: £139.00 for four weekly doses.
0.5 mg Cost: £179.00
Over the following four weeks, the dose may be increased to 0.5 mg once weekly to enhance appetite suppression and support better portion control as tolerance improves. Cost: £179.00 for four weekly doses.
1.0 mg Cost: £187.00
By weeks 9 to 12, treatment may progress to a 1.0 mg weekly dose, providing stronger appetite regulation and continued support for weight-management goals. Cost: £187.00 for four weekly doses.
1.7 mg Cost: £237.00
During weeks 13 to 16, the dose may be increased further to 1.7 mg once weekly, helping to strengthen metabolic balance and appetite control under clinical guidance. Cost: £237.00 for four weekly doses.
2.4 mg Cost: £287.00
From week 17 onwards, and once suitability is confirmed, treatment may continue with the 2.4 mg once-weekly maintenance dose, which supports long-term weight management and sustained appetite control. Cost: £287.00 for four weekly doses.
How to use Wegovy pens?
Wegovy is administered once a week as an injection beneath the skin and does not depend on meal timing. Selecting a fixed day each week helps build consistency and supports regular use. Each weight loss pen is designed to provide four weekly doses, covering a full month of treatment. After the final dose is used, a new pen is required for the next treatment period.
Before giving your injection, take a few moments to prepare properly to ensure safe and accurate use.
- Verify your medication: Check the pen label carefully to confirm it matches your prescribed Wegovy strength and dosage.
- Inspect the solution: Remove the pen cap and view the liquid inside the pen window. The solution should appear clear and colourless. Do not use the pen if you notice cloudiness or visible particles.
- Attach a new needle: Use a new needle for every injection. Twist it securely onto the pen to ensure correct delivery.
- Perform a flow check (first use only): When using a new pen for the first time, remove both needle caps and complete the flow check as instructed in the patient information leaflet to confirm the pen is working correctly.
- Set your dose: Turn the dose selector until your prescribed dose is clearly shown in the display window.
- Select an injection site: Inject into the abdomen (avoiding the area within 5cm of the belly button), thigh, or upper arm. Rotate injection sites each week to help reduce skin irritation and support consistent absorption.
- Give the injection: Insert the needle straight into the skin and keep the dose window visible while the medication is delivered.
- Dispose of used items safely: After the injection, place the outer needle cap back on, remove the needle carefully, and dispose of the needle and cap in a sharps container.
How to use the Wegovy: Step-by-step video guide
A video guide is available to demonstrate correct preparation and injection technique. It shows each step clearly, helping you feel confident using the pen at home while following safe injection practices.
Still have questions? Contact us or call (020) 7550 6515
Where should Wegovy be injected?
Wegovy for weight loss is injected just under the skin into areas with adequate fatty tissue. Suitable sites include the abdomen, thighs, or upper arms. Rotating injection areas each week helps protect the skin and improves comfort.
Using different sites regularly also supports consistent absorption. Avoid injecting into the same exact spot repeatedly, even within the same area.
Choose an area: abdomen or thighs.
Select a site for administering the shot.
Make four divisions on the site. Inject into one division per week.
When injecting into the abdomen ensure a 5 cm distance from the navel.
Table of Contents
- What should I do if I miss a dose of Wegovy?
- Wegovy Interactions with other medication
- Who should not take Wegovy?
- Side effects of Wegovy
- How to reduce and manage Wegovy side effects?
- Wegovy warnings
- Does Wegovy have heart health benefits?
- Comparing wegovy with alternative weight loss treatments
- Where Can I Buy Wegovy Online UK
- What to expect after stopping Wegovy?
What should I do if I miss a dose of Wegovy?
If you miss a dose, timing determines the next step. When fewer than five days have passed since your scheduled injection, take the missed dose as soon as possible and continue on your usual day. If more than five days have passed, skip the missed dose and wait for your next scheduled injection.
Do not take double doses, as this increases side-effect risk without improving results. If you miss two or more doses, speak with our clinical team. They may advise restarting the weight loss shot Wegovy at a lower dose, particularly if digestive side effects occurred previously.
Wegovy Interactions with other medication
Before starting Wegovy injection, share a complete list of all medicines you use, including supplements and over-the-counter products. This allows clinical team to identify interactions and plan treatment safely.
Extra monitoring is required for people using insulin or sulfonylureas, as combining these with Wegovy for weight loss can increase the risk of low blood sugar. The weight loss medication should not be used alongside other GLP-1 receptor agonists, such as Mounjaro or liraglutide, due to increased side-effect risk.
Who should not take Wegovy?
Do not start Wegovy weight loss injections if you are pregnant, planning to become pregnant, or breastfeeding. Current evidence does not confirm its safety during pregnancy or while nursing, so healthcare professionals advise against use during these periods. The weight loss pen is also not usually prescribed for people with a BMI below 27 unless a clinically recognised weight-related condition is present.
Avoid weight loss injection if you have ever had a severe allergic reaction to semaglutide or any ingredient used in the injection. Certain medical conditions also require careful assessment before treatment. These include diabetic eye disease, a previous episode of pancreatitis, or advanced heart failure, where closer monitoring or alternative options may be more appropriate.
The clinical team must review your medical history before treatment if you have:
- Kidney disease
- Diabetes
- A history of pancreatitis
- Previous episodes of low blood sugar
- Diabetic retinopathy
Some medicines can interfere with how Wegovy works or increase the chance of side effects. This includes other GLP-1–based treatments such as Saxenda or Mounjaro, as well as diabetes medicines like insulin or sulfonylureas. In these cases, the clinical team may adjust doses, monitoring, or treatment plans to maintain safety.
Always provide a full list of medicines and supplements you use, including non-prescription and herbal products. The healthcare professionals use this information to confirm whether Wegovy is appropriate for you. Treatment only begins after a full medical consultation confirms it is appropriate.
Side effects of Wegovy
Not everyone experiences side effects while using Wegovy for weight loss. When symptoms occur, they often appear during treatment initiation or dose increases and usually improve as the body adjusts.
Very common side effects of Wegovy
These effects are reported most frequently, especially during the early stages of treatment:
- Nausea or vomiting
- Headache
- Diarrhoea
- Constipation
- Abdominal discomfort or pain
- Tiredness or general weakness
Common side effects of Wegovy
Some individuals may also notice:
- Indigestion or bloating
- Gas or reflux
- Hair thinning
- Injection site reactions
- Gallstones
- Gastritis
- Low blood sugar in people using diabetes medicines
- Changes in taste
Uncommon side effects of Wegovy
Less frequently reported effects include:
- Increased heart rate
- Raised pancreatic enzymes
- Slowed stomach emptying
- Low blood sugar without diabetes
- Raised bilirubin levels
Rare side effects
Although uncommon, some side effects require urgent medical attention. These include:
- Worsening of diabetic eye disease (diabetic retinopathy)
- Severe or persistent pain in the abdomen or back, which may indicate pancreatitis
- Kidney or bladder stones, sometimes causing sharp pain, urinary changes, or difficulty passing urine
- Allergic reactions such as swelling of the face or throat, breathing difficulties, dizziness, or hives
- Increased risk of bone fractures, particularly in people with reduced bone strength
- Bowel obstruction, which may present as severe constipation, bloating, and vomiting
- Always read the patient information leaflet and seek medical advice if symptoms persist or worsen.
How to reduce and manage Wegovy side effects?
Most people experience mild side effects when starting Wegovy, and these often improve as the body adjusts. You can reduce discomfort by staying well hydrated, choosing easily digested foods, and spreading meals into smaller portions throughout the day. These adjustments help ease nausea and digestive symptoms during treatment.
If side effects continue, become more noticeable, or begin to interfere with daily life, you should contact a healthcare professional for guidance. Seek urgent medical attention if you develop severe abdominal pain, breathing problems, or swelling of the face, lips, or throat, as these may signal a serious reaction.
Many people tolerate Wegovy without difficulty and continue treatment comfortably. The weight loss injection supports weight management over time, and side effects usually remain manageable with the right support.
Wegovy warnings
Do not use Wegovy if you have a known allergy to semaglutide or any ingredient in the injection. Before starting treatment, speak with a healthcare professional if you have kidney disease, diabetes, or a previous episode of pancreatitis.
You should also seek medical advice if you have diabetic retinopathy or expect to undergo surgery requiring anaesthesia. Always inform our clinical team if you take other medicines, particularly insulin, sulfonylureas, or other weight-loss injections such as Saxenda or Mounjaro.
Wegovy and pregnancy
Do not use Wegovy during pregnancy or when planning to become pregnant. Stop treatment at least two months before trying to conceive. If you suspect pregnancy at any point, discontinue Wegovy and seek medical advice promptly.
Wegovy and breastfeeding
Do not use Wegovy while breastfeeding. Current evidence does not confirm whether semaglutide passes into breast milk or how it may affect a nursing infant.
Contraception
Use reliable contraception while taking Wegovy. Although the medication does not directly affect oral contraceptives, vomiting or diarrhoea may reduce absorption. In these cases, a clinician may recommend additional or alternative contraception methods.
Does Wegovy have heart health benefits?
Wegovy is approved by the MHRA in the UK for obesity management and has additional relevance for cardiovascular health. Clinical evidence suggests that weight loss achieved with Wegovy may lower the risk of major cardiovascular events, including heart attack and stroke, in people with obesity and related risk factors.
Comparing Wegovy with alternative weight loss treatments
| Feature | Wegovy | Mounjaro | Saxenda |
|---|---|---|---|
| Main ingredient | Semaglutide | Tirzepatide | Liraglutide |
| How it supports weight loss | Helps control hunger signals, slows digestion, and you feeling full for longer | Target appetite control, delays digestion, increases fullness, and supports blood sugar regulation | Suppresses appetite, slow digestion, and enhances feelings of fullness |
| Dose progression | Dose increases in 4-week stages | Dose increases in 4-week stages | Dose increases weekly |
| Dosing frequency | Injected once per week | Injected once per week | Injected once per day |
| Weight loss results in studies | Participants achieved weight loss of up to 15% | Participants achieved weight loss of up to 20% | Participants achieved weight loss of around 5–10% |
| Prescription required | Yes | Yes | Yes |
Where Can I Buy Wegovy Online UK
Wegovy can only be bought online in the UK through a regulated clinic that provides a prescription after a clinical assessment. If you are looking to buy Wegovy online UK, it must first be approved by a licensed healthcare professional to confirm it is safe and suitable for you. This ensures you receive genuine Wegovy supplied through an authorised UK pharmacy under proper medical supervision.
You can buy Wegovy online from Mayfair Weight Loss Clinic through a fully supervised and regulated prescribing process. Patients complete a free online consulation form, and once approved, receive Wegovy UK supplied by a registered pharmacy. The clinic also provides dosing guidance and ongoing clinical support, ensuring safe access to treatment under professional medical supervision.
Choosing Mayfair Weight Loss Clinic allows patients to buy Wegovy online in the UK with confidence, knowing the treatment is authentic, clinically approved, and supported by qualified prescribers. This structured approach ensures safe access to Wegovy while helping patients progress through treatment under proper medical supervision.
Cost of Wegovy UK
Wegovy pricing in the UK varies depending on the prescribed dose and treatment stage. At Mayfair Weight Loss Clinic, all prices include regulated prescribing, genuine medication, and full clinical supervision to ensure safe and authentic treatment.
Wegovy cost list
- Wegovy 0.25 mg (4 Weeks): £139.00
- Wegovy 0.5 mg (4 Weeks): £179.00
- Wegovy 1.0 mg (4 Weeks): £187.00
- Wegovy 1.7 mg (4 Weeks): £237.00
- Wegovy 2.4 mg (4 Weeks+): £287.00
For optimal results, Wegovy should be combined with a balanced diet and regular exercise.
Where to get Wegovy prescription online
You can get Wegovy prescription online from Mayfair Weight Loss Clinic through a fully supervised clinical process. Patients complete a medical consultation, and once approved, receive a regulated prescription and genuine Wegovy dispensed by a registered pharmacy. The clinic also provides dosing guidance and ongoing clinical support, ensuring safe and medically supervised access to Wegovy treatment in the UK.
How to get Wegovy treatment at Mayfair Weight Loss Clinic
To get Wegovy from Mayfair Weight Loss please follow the following steps:
- Complete a clinical assessment to confirm eligibility based on BMI, medical history, and treatment suitability.
- A licensed prescriber reviews your information to ensure Wegovy is safe and appropriate for you.
- Once approved, your Wegovy prescription is issued and dispensed through a registered UK pharmacy.
- Receive clear guidance on dosing, injection use, and safe treatment progression.
- Access ongoing clinical support and monitoring throughout your Wegovy treatment journey.
What to expect after stopping Wegovy?
Wegovy does not cause dependence, and treatment can stop once a healthy weight or BMI is achieved. After discontinuation, appetite regulation gradually decreases, and hunger levels may rise. Clinical research shows that weight regain commonly occurs without ongoing lifestyle support, with some individuals regaining a significant portion of lost weight within a year.
Maintaining results after stopping Wegovy requires continued attention to diet and physical activity. While stopping treatment does not cause withdrawal symptoms, stepping away from healthy routines increases the risk of weight regain. Consistent habits remain essential for long-term weight management.
What our customers say
We pride ourselves on great customer service. Here are some comments left by our customers.
Michelle
Very easy and quick consultation process. Weight loss pens arrived the next day.
Mary
Friendly customer service team, responded promptly and professionally to my questions.
Amy
Ordered on Tuesday and it arrived on Wednesday morning. Very well packed. Excellent service.
FAQs
- Complete the confidential online consultation form
- Provide details about your health history and weight goals
- A licensed prescriber reviews your assessment
- If appropriate, Wegovy or an alternative may be recommended
- Once approved, your prescription is issued
- Your medication is delivered discreetly to your home
The most common side effects include:
- Mild nausea
- Bloating
- Constipation
- Fatigue (especially in the early weeks of treatment)
These effects often improve as treatment continues. Support is available for managing symptoms.
If you are currently using Saxenda or have used it previously, the following guidance applies:
- If you are taking Saxenda 3.0mg once daily: You may switch to Wegovy 0.5mg once weekly. Although both medicines belong to the GLP-1 class, they contain different active ingredients. Starting at 0.5mg helps reduce the risk of side effects. After four weeks, the dose may be increased gradually in line with prescribing guidance.
- If you are taking a lower dose than 3.0mg of Saxenda: You should start Wegovy at 0.25mg.
- If you previously used Saxenda but had a long break in treatment: Restarting at 0.25mg Wegovy is advised to improve tolerability.
Fatigue (especially in the early weeks of treatment) These effects often improve as treatment continues. Support is available for managing symptoms.
If you are currently using Ozempic or have used it previously for weight loss, the following guidance applies:
- If you are currently taking Ozempic: You may switch to the equivalent dose of Wegovy or the next dose level. For example, if you are on 1.0mg Ozempic, you may move to 1.7mg Wegovy.
- If you have had a short treatment gap of a few weeks: You may continue Wegovy at the dose you previously reached.
- If you were previously taking Ozempic 1.0mg and had a longer break: Restarting Wegovy at 0.5mg is recommended to reduce the risk of side effects such as nausea.
- If Ozempic is prescribed for type 2 diabetes: You should continue using Ozempic and not switch to Wegovy. Wegovy is not licensed for diabetes management.
If you are switching from Ozempic used for weight loss, the same guidance applies:
- If you are currently on Ozempic: You may switch to the same or next higher dose of Wegovy.
- If you had a short break in treatment: You may continue from your previous dose level.
- If you had a longer treatment gap: Restarting at 0.5mg Wegovy is safer and helps reduce side effects.
If Ozempic is being used for type 2 diabetes, you should not switch to Wegovy. Switching from Saxenda to Wegovy (summary guidance)
- Saxenda 3.0mg daily → Wegovy 0.5mg weekly
- Lower Saxenda dose → Wegovy 0.25mg
- Long gap after Saxenda → Wegovy 0.25mg
Dose increases should follow manufacturer guidance and clinical advice.
- Ongoing review and support from UK-licensed clinicians
- Online consultations designed to fit around your schedule
- Guidance on nutrition alongside medication use
- Discreet delivery to your home
- Clear pricing with no unexpected costs
- Needles provided at no charge, with sharps bins available if required
Here's how you can easily order Wegovy from Mayfair:
- Complete the confidential online consultation form
- Provide details about your health history and weight goals
- Guidance on nutrition alongside medication use
- A licensed prescriber reviews your assessment
- If appropriate, Wegovy or an alternative may be recommended
- Once approved, your prescription is issued
- Your medication is delivered discreetly to your home
Reviewed By: Dr. John Lekkas
GMC Registration: 7448560
Dr John Lekkas is a GMC registered medical doctor with a specialist PhD, and is a global leading expert in weight loss and aesthetic medicine.
Last reviewed on: 20/02/2026Start free Consultation
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