In the UK, prices for Mounjaro (Tirzepatide) injections are expected to rise from September, making patients consider switching from Mounjaro (Tirzepatide) to a more cost-effective alternative, Wegovy (Semaglutide).

If you are looking for a safe and easy way to continue your weight loss journey, this guide will help you by answering the most common questions regarding the transition.

Key Takeaways

● Mounjaro (Tirzepatide) and Wegovy (Semaglutide) are weight loss medications, both of which fall under the GLP-1 agonist category. These medications work by lowering appetite and prolonging satiety. Unlike Wegovy (Semaglutide), Mounjaro (Tirzepatide) targets an additional receptor: GIP. That means it also regulates blood sugar levels while promoting a lower appetite.

● Mounjaro (Tirzepatide) is available in 6 doses, with 2.5mg being the lowest and 15mg being the highest. Wegovy (Semaglutide) is available in 5 doses, with 0.25mg being the lowest and 2.4mg being the highest.

● Switching from Mounjaro (Tirzepatide) to Wegovy (Semaglutide) is a personal decision that must be taken after careful consideration and a doctor-advised regimen.

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Is It Safe to Switch from Mounjaro to Wegovy?

Yes. Transitioning from Mounjaro (Tirzepatide) to Wegovy (Semaglutide) is completely safe. However, it should be observed under the guidance of a medical expert.

Can I Switch to Wegovy If My BMI is Below 27?

Yes, in some cases. If you’ve already been using Mounjaro (Tirzepatide) and have reached your goal weight or you’re now focused on maintaining it, Wegovy (Semaglutide) may still be an option.

When to Start Wegovy after Stopping Mounjaro?

Wait at least 7 days after your last Mounjaro dose before starting Wegovy. This “wash-out” period allows your body to adjust and helps prevent side effects.

What to Expect After Switching from Mounjaro to Wegovy?

Every patient’s experience is a little different, but there are some common things to be aware of:

Starting point varies: Depending on your previous Mounjaro dose, you may begin anywhere between 0.25mg and 1mg of Wegovy.

Adjustment period: Wegovy’s effects tend to build gradually, so appetite control may feel different at first.

Therapeutic balance: With consistent use, most patients find their hunger and weight loss stabilize as Wegovy reaches effective levels.

Possible side effects: Some people experience mild digestive symptoms early on, which usually ease with time.

Our Mounjaro to Wegovy Conversion Guide

When switching from Mounjaro (Tirzepatide) to Wegovy (Semaglutide), it is not possible to make an “mg-mg” switch. To begin Wegovy (Semaglutide), follow the following conversion guide:

Current Mounjaro Dose Typical Starting Wegovy Dose*
2.5mg 0.25mg
5mg 0.5mg
7.5mg 1mg
10mg 1mg
12.5mg 1mg
15mg 1mg

*Your exact starting dose may differ depending on your medical history, side effect profile, and previous weight loss.

The above conversion is a general guideline. It may differ based on medical history and treatment progress. It is best to comply with a medical expert’s prescribed dosage.

Do I Have to Start at a Lower Dose of Wegovy?

Not always. Your Wegovy starting dose is guided by the dose of Mounjaro you’ve been taking. For instance, someone on 2.5mg of Mounjaro might be started on Wegovy 0.25mg, while patients on higher Mounjaro doses (such as 7.5mg or more) are often transitioned straight to 1mg of Wegovy.

Your provider will decide the most appropriate starting point based on your medical profile, how you’ve tolerated treatment, and your progress so far.

Can I Switch Back to Mounjaro Later?

In most cases, returning to Mounjaro (Tirzepatide) is possible after switching to Wegovy (Semaglutide). But medical supervision is always advised. If your medical supervisor thinks it’s safe to do so, you can switch back to Mounjaro (Tirzepatide).

Are There Any Withdrawal Symptoms When Switching from Mounjaro to Wegovy?

No. There are no such withdrawal symptoms associated with switching from Mounjaro (Tirzepatide) to Wegovy (Semaglutide). Appetite increase is likely to occur once Mounjaro’s effects wear off. However, starting Wegovy (Semaglutide) after the ‘wash out’ period keeps the appetite under control.

Will I Experience Weight Gain During the Switch?

No. It is unlikely to happen because after stopping Mounjaro (Tirzepatide), the drug remains in your body during the wash-out period. Once the wash-out period is over, you’ll immediately start on Wegovy (Semaglutide). This will keep your appetite, and ultimately your weight, under control.

Support with Switching from Mounjaro to Wegovy

Switching from Mounjaro (Tirzepatide) to Wegovy (Semaglutide) is safe if you are considering doing so. Both medications have demonstrated effectiveness for weight loss during clinical trials. If you’re interested in making a switch, you can start your Wegovy online consultation today.